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HIV Hidden in Patients’ Cells Can Now Be Accurately Measured

HIV Hidden in Patients’ Cells Can Now Be Accurately Measured

This human T cell (blue) is under attack by HIV (yellow), the virus that causes AIDS. The virus specifically targets T cells, which play a critical role in the body's immune response against invaders like bacteria and viruses. Credit: Seth Pincus, Elizabeth Fischer and Austin Athman, National Institute of Allergy and Infectious Diseases, National Institutes of Health.

Until now, researchers haven't been able to accurately quantify a latent form of HIV that persists in patients' immune cells. This hampers doctors' ability to assess the effectiveness of a particular treatment and select better alternatives.

Scientists Uncover RNA Silencing Technique to Change Seed Size in Plants

Scientists Uncover RNA Silencing Technique to Change Seed Size in Plants

In a development with promising implications for crop farmers in the U.S. and around the world, scientists at The University of Texas at Austin have figured out how to get some plants to produce nearly one-third bigger seeds.

Scientists Coax Proteins to Form Synthetic Structures with Method that Mimics Nature

Scientists Coax Proteins to Form Synthetic Structures with Method that Mimics Nature

As a proof of concept, a team of researchers at the University of Texas at Austin built tiny structures that resemble two doughnuts stacked on top of each other by applying electrical charges to specific spots on naturally occurring proteins. Credit: University of Texas at Austin.

Scientists have long dreamed of creating synthetic structures out of the same raw material that nature uses in living systems — proteins — believing such an advance would allow for the development of transformative nanomachines, for example, molecular cages that precisely deliver chemotherapy drugs to tumors or photosynthetic systems for harvesting energy from light. Now a team of biologists from The University of Texas at Austin and the University of Michigan have invented a way to build synthetic structures from proteins, and just as in nature, the method is simple and could be used for a variety of purposes.

Bacteria Help Scientists Discover Human Cancer-Causing Proteins

Bacteria Help Scientists Discover Human Cancer-Causing Proteins

Researchers genetically modified E coli bacteria to fluoresce red when DNA was damaged. Then, they overexpressed each of the bacteria’s 4,000 genes individually and determined which proteins made bacteria glow red. With these bacterial proteins as a guide, they identified more than 100 analogous human proteins that are now implicated in DNA damage and initiation of cancer. Image credit: Jun Xia.

A team led by researchers at The University of Texas at Austin and Baylor College of Medicine has applied an unconventional approach involving bacteria to discover human proteins that can lead to DNA damage and promote cancer. This could lead to new tests to identify people who are likely to develop cancer. Reported in the journal Cell, the study also proposes biological mechanisms by which these proteins can damage DNA, opening possibilities for future cancer treatments.

Two UT Scientists Part of Project to Detect ‘Life As We Don’t Know It’

Two UT Scientists Part of Project to Detect ‘Life As We Don’t Know It’

Eric Anslyn and Andrew Ellington.

A nearly $7 million grant from NASA is supporting research to develop approaches to detecting extraterrestrial life, and two University of Texas at Austin faculty are part of the interdisciplinary scientific team.

18 Notable and Newsworthy Texas Science Stories from 2018

18 Notable and Newsworthy Texas Science Stories from 2018

It's been a big year for Texas Science, with news about research, new discoveries, technological advancements and awards making headlines around the world. Here are a few UT Austin science stories that made the news in 2018.

UT Scientists, Mathematicians and High Schoolers Partner for Success

UT Scientists, Mathematicians and High Schoolers Partner for Success

Gold medalists in an astrophysics Olympic-style event, award-winners at a statewide science fair and budding genetic engineers who shared their research 2,000 miles away are among the high schoolers who found success after working closely with members of the Texas Science community in 2018.

New Flu Drug Informed by UT Austin Professor's 40-year-old Basic Research

New Flu Drug Informed by UT Austin Professor's 40-year-old Basic Research

Last year, Texas saw a particularly deadly flu season. Now, there is a new Federal Drug Administration-approved treatment, Xofluza, designed to catch the flu in its early stages and stop it from spreading. The drug is thanks in large part to professor emeritus Robert Krug's basic research, undertaken almost 40 years ago.

New Protein Sequencing Method Could Transform Biological Research

New Protein Sequencing Method Could Transform Biological Research

An ultra-sensitive new method for identifying the series of amino acids in individual proteins (a.k.a. protein sequencing) can accelerate research on biomarkers for cancer and other diseases. Credit: David Steadman/University of Texas at Austin.

A team of researchers at The University of Texas at Austin has demonstrated a new way to sequence proteins that is much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time. The advance could have a major impact in biomedical research, making it easier to reveal new biomarkers for the diagnosis of cancer and other diseases, as well as enhance our understanding of how healthy cells function.

Visualizing Science 2018: Beauty and Inspiration in College Research

Visualizing Science 2018: Beauty and Inspiration in College Research

Over the last six years, faculty, staff and students from across the College of Natural Sciences have submitted hundreds of images from their scholarly research for our annual Visualizing Science competition, and these images have been viewed by tens of thousands of people. The submitted images, often beautiful and stunning, are the ones that spoke to their creators, inspiring and informing them as they followed their scientific passions.