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DNA Barcodes That Reliably Work: A Game-Changer for Biomedical Research

DNA Barcodes That Reliably Work: A Game-Changer for Biomedical Research

This illustration shows the most common structure of DNA found in a cell, called B-DNA. Credit: Richard Wheeler (Zephyris). Used under the Creative Commons Attribution-ShareAlike 3.0 license.

In the same way that barcodes on your groceries help stores know what's in your cart, DNA barcodes help biologists attach genetic labels to biological molecules to do their own tracking during research, including of how a cancerous tumor evolves, how organs develop or which drug candidates actually work. Unfortunately with current methods, many DNA barcodes have a reliability problem much worse than your corner grocer's. They contain errors about 10 percent of the time, making interpreting data tricky and limiting the kinds of experiments that can be reliably done.

A Change in Bacteria’s Genetic Code Holds Promise of Longer-Lasting Drugs

A Change in Bacteria’s Genetic Code Holds Promise of Longer-Lasting Drugs

An alteration in the genetic code of bacteria holds promise for protein therapeutics. Credit: University of Texas at Austin.

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

James Allison Eases Off the Brakes (Audio)

James Allison Eases Off the Brakes (Audio)

Forty years ago, when James Allison had just gotten his PhD in biochemistry, he was intrigued by this far-out idea that was floating around about a new way to treat cancer. The idea—dubbed cancer immunotherapy—was to train the body's immune system to attack cancer cells—the same way this system already goes after bacteria and viruses. He was one of the few people who actually believed it could work.

Eight students receive prestigious NSF Graduate Research Fellowships

Eight students receive prestigious NSF Graduate Research Fellowships

Four graduate students and four undergraduates have received prestigious NSF Graduate Fellowships.

​The National Science Foundation (NSF) has awarded the prestigious Graduate Research Fellowship to 30 University of Texas at Austin students, including four graduate students and four undergraduates from the College of Natural Sciences.

Paul Goldbart Appointed Dean of UT Austin’s College of Natural Sciences

Paul Goldbart Appointed Dean of UT Austin’s College of Natural Sciences

Paul Goldbart

The University of Texas at Austin has named Paul Goldbart the next dean of the College of Natural Sciences. His appointment will begin Aug. 1, and he will hold the Robert E. Boyer Chair in Natural Sciences.

The 40 Year-old Discovery Behind A Promising New Flu Drug

The 40 Year-old Discovery Behind A Promising New Flu Drug

A discovery that Robert Krug, a University of Texas at Austin molecular biologist, made decades ago has led to the development of a new drug to fight flu infections more effectively than existing drug treatments.

Cancer Agency Awards More than $3 Million to University of Texas at Austin Scientists

Cancer Agency Awards More than $3 Million to University of Texas at Austin Scientists

Three awards totaling $3.19 million from the Cancer Prevention and Research Institute of Texas (CPRIT) will support cancer research in The University of Texas at Austin's Departments of Molecular Biosciences and Chemistry.

The Future of Science All in One Room

The Future of Science All in One Room

Researchers from across the world are coming to Austin this week for one of the most important scientific gatherings of the year — the 2018 AAAS (American Association for the Advancement of Science) Annual Meeting. Among them are some remarkable undergraduate students from The University of Texas at Austin who will be presenting original research at the conference.

Alumna Tackles Disparities in Cancer Treatment

Alumna Tackles Disparities in Cancer Treatment

Leticia Nogueira. Photo credit: Vivian Abagiu.

Leticia Nogueira, Director of Health Services at the American Cancer Society, received her PhD in Molecular Biology at the University of Texas at Austin in 2010.

Promise of New Antibiotics Lies with Shackling Tiny Toxic Tetherballs to Bacteria

Promise of New Antibiotics Lies with Shackling Tiny Toxic Tetherballs to Bacteria

Biologists at The University of Texas at Austin have developed a method for rapidly screening hundreds of thousands of potential drugs for fighting infections, an innovation that holds promise for combating the growing scourge of antibiotic-resistant bacteria. The method involves engineering bacteria to produce and test molecules that are potentially toxic to themselves.