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Ancient Enzyme Could Boost Power of Liquid Biopsies to Detect and Profile Cancers

Ancient Enzyme Could Boost Power of Liquid Biopsies to Detect and Profile Cancers

Scientists are developing a set of medical tests called liquid biopsies that can rapidly detect the presence of cancers, infectious diseases and other conditions from only a small blood sample. Researchers at The University of Texas at Austin are developing a new tool for liquid biopsy that could soon provide doctors with a more complete picture of an individual's disease, improving their chances of finding the best treatment, while also sparing patients the pain, inconvenience and long wait times associated with surgical biopsies.

Stone Named Emerging Inventor of the Year

Stone Named Emerging Inventor of the Year

Everett Stone, a research assistant professor in the Department of Molecular Biosciences at The University of Texas at Austin, has been named the 2017 Emerging Inventor of the Year by the university's Office of Technology Commercialization. The award is given to recognize faculty members who excel in their fields and whose work produces practicable innovations and life-changing discoveries.

Chemists Receive $2 Million to Develop Inexpensive Home Test for Heart Failure

Chemists Receive $2 Million to Develop Inexpensive Home Test for Heart Failure

With the prick of a finger, the new sensor could indicate whether a person has elevated levels of a biomarker associated with heart failure. Credit: iStock.

The National Institutes of Health (NIH) has awarded a team led by Richard M. Crooks, a chemistry professor at The University of Texas at Austin, a $2 million grant to develop an inexpensive, at-home test for people diagnosed with heart failure.

Why Poison Frogs Don’t Poison Themselves

Why Poison Frogs Don’t Poison Themselves

The phantasmal poison frog, Epipedobates anthonyi, is the original source of epibatidine, discovered by John Daly in 1974. Epibatidine has not been found in any animal outside of Ecuador, and its ultimate source, proposed to be an arthropod, remains unknown. This frog was captured at a banana plantation in the Azuay province in southern Ecuador in August 2017. Credit: Rebecca Tarvin/University of Texas at Austin.

Don't let their appearance fool you: Thimble-sized, dappled in cheerful colors and squishy, poison frogs in fact harbor some of the most potent neurotoxins we know. With a new paper published in the journal Science, scientists are a step closer to resolving a related head-scratcher — how do these frogs keep from poisoning themselves? And the answer has potential consequences for the fight against pain and addiction.

Scientist Battling Invincible Microbes Takes Fight to the Silver Screen

Scientist Battling Invincible Microbes Takes Fight to the Silver Screen

Bryan Davies is an assistant professor in molecular biosciences and biotechnologist at the University of Texas at Austin, leading research into how to combat antibiotic-resistant bacteria and develop new antimicrobials to fight infection.

Couples Weather Bickering With a Little Help from Their Friends

Couples Weather Bickering With a Little Help from Their Friends

Every couple has conflict, and new research finds that having good friends and family members to turn to alleviates the stress of everyday conflict between partners. In fact, according to the study led by The University of Texas at Austin's Lisa Neff, social networks may help provide protection against health problems brought about by ordinary tension between spouses.

Scientists: New Device Accurately Identifies Cancer in Seconds (Updated)

Scientists: New Device Accurately Identifies Cancer in Seconds (Updated)

A team of scientists and engineers at The University of Texas at Austin has invented a powerful tool that rapidly and accurately identifies cancerous tissue during surgery, delivering results in about 10 seconds—more than 150 times as fast as existing technology. The MasSpec Pen is an innovative handheld instrument that gives surgeons precise diagnostic information about what tissue to cut or preserve, helping improve treatment and reduce the chances of cancer recurrence.

Scientists Discover Powerful Potential Pain Reliever

Scientists Discover Powerful Potential Pain Reliever

Stephen Martin (left) and James Sahn have discovered a new pain reliever that acts on a previously unknown pain pathway. Photo Credit: Courtesy of Stephen Martin.

A team of scientists led by chemists Stephen Martin and James Sahn at The University of Texas at Austin have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway. The synthetic compound, known as UKH-1114, is as effective at relieving neuropathic pain in injured mice as a drug widely used for pain relief called gabapentin, but it works at a much lower dose, with longer duration of action.

New Technique Enables Safer Gene-Editing Therapy Using CRISPR

New Technique Enables Safer Gene-Editing Therapy Using CRISPR

A CRISPR protein targets specific sections of DNA and cuts them. Scientists have turned this natural defense mechanism in bacteria into a tool for gene editing. Illustration: Jenna Luecke and David Steadman/Univ. of Texas at Austin.

Scientists from The University of Texas at Austin took an important step toward safer gene-editing cures for life-threatening disorders, from cancer to HIV to Huntington's disease, by developing a technique that can spot editing mistakes a popular tool known as CRISPR makes to an individual's genome. The research appears today in the journal Cell.

Chemist Searches for Less Toxic Compound to Preserve Organs

Chemist Searches for Less Toxic Compound to Preserve Organs

A computer simulation shows how DMSO molecules (red, white and yellow) form hydrogen bonds with water molecules (red and white). Credit: Carlos Baiz.

About a third of all deaths in the U.S. could be prevented or substantially delayed by organ transplantation, according to a 2015 report from the U.S. military. The main bottleneck is that there is no practical way to preserve organs for more than a few hours. If you try to freeze a whole organ, water within and between cells forms ice crystals that cause the cells to rupture.